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Digitalis (/ ˌ d ɪ dʒ ɪ ˈ t eɪ l ɪ s / [3] or / ˌ d ɪ dʒ ɪ ˈ t æ l ɪ s / [4]) is a genus of about 20 species of herbaceous perennial plants, shrubs, and biennials, commonly called foxgloves. Digitalis is native to Europe, Western Asia, and northwestern Africa. The flowers are tubular in shape, produced on a tall spike, and vary in ...
May worsen hormone sensitive conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis, and uterine fibroids. [17] Insomnia. [17] Goldenseal: orangeroot, yellow puccoon Hydrastis canadensis: Uterotonic [3] Greater celandine: celandine Chelidonium majus: Liver damage [4] Guarana: Paullinia cupana: Agitation and insomnia [3 ...
Digoxin has the ability to bind oestrogen receptors, and therefore it has been proposed that it might increase the risk of oestrogen-sensitive breast and uterine cancers. [62] A large Danish study found a complicated picture, with slightly increased risk of breast cancer amongst women taking digoxin, but better prognostic features. [63]
It came into use in treating cardiac disease in late 18th century England in spite of its high toxicity. a Its use has been almost entirely replaced by the pharmaceutical derivative Digoxin, which has a shorter half-life in the body, and whose toxicity is therefore more easily managed. [54] Digoxin is used as an antiarrhythmic agent and ...
Digitalis purpurea, the foxglove or common foxglove, is a toxic species of flowering plant in the plantain family Plantaginaceae, [2] native to and widespread throughout most of temperate Europe. [3] It has also naturalized in parts of North America, as well as some other temperate regions.
The general structure of a cardiac glycoside consists of a steroid molecule attached to a sugar and an R group. [4] The steroid nucleus consists of four fused rings to which other functional groups such as methyl, hydroxyl, and aldehyde groups can be attached to influence the overall molecule's biological activity. [4]
Digitalis obscura is a shrub or herbaceous perennial growing from a woody base, reaching 1 to 3.9 feet (0.30 to 1.19 m) tall. [6] The stems are smooth and erect. The long leaves are basal and form in a rosette fashion, growing outward closer to the ground.
Digitalis thapsi is an endemic species of the Iberian Peninsula, [4] [6] occurring in both Portugal and Spain. It grows in the mountains and rocky plains of the central and central-western parts of the Iberian Peninsula, especially in the Sistema Central and its extensions between the rivers of the Douro and Tagus .