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An immature teratoma is a teratoma that contains anaplastic immature elements, and is often synonymous with malignant teratoma. [1] A teratoma is a tumor of germ cell origin, containing tissues from more than one germ cell line, [2] [3] [4] It can be ovarian or testicular in its origin.
Teratoma are most common germ cell tumor of ovary. Teratomas can be divided into two types: mature teratoma (benign) and immature teratoma (malignant). Immature teratomas contain immature or embryonic tissue which significantly differentiates them from mature teratomas as they carry dermoid cysts. [5]
Ovarian tumors by incidence and risk of ovarian cancer, with mature cystic teratoma at bottom and immature teratoma at right. [55] Embryonal teratomas most commonly occur in the sacrococcygeal region; sacrococcygeal teratoma is the single most common tumor found in newborn humans.
Polyembryomas, the most immature form of teratoma and very rare ovarian tumors, are histologically characterized by having several embryo-like bodies with structures resembling a germ disk, yolk sac, and amniotic sac. Syncytiotrophoblast giant cells also occur in polyembryomas. [32]
Mature cystic teratoma: 46.0%: 0.17% to 2% [6] Cystic, with elements of all 3 germ layers (endoderm, mesoderm and ectoderm). [7] Hair follicles. Immature teratoma: 2.5%: 100%: A teratoma that contains anaplastic immature elements, and is often synonymous with malignant teratoma. [8] Other germ cell tumors 3.0%
pelvis, particularly sacrococcygeal teratoma; In females, GCTs account for 30% of ovarian tumors, but only 1 to 3% of ovarian cancers in North America. In younger women, they are more common, thus in patients under the age of 21, 60% of ovarian tumors are of the germ-cell type, and up to one-third are malignant.
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A dermoid cyst is a teratoma of a cystic nature that contains an array of developmentally mature, solid tissues. It frequently consists of skin, hair follicles, and sweat glands, while other commonly found components include clumps of long hair, pockets of sebum, blood, fat, bone, nail, teeth, eyes, cartilage, and thyroid tissue.