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Sarcoidosis, an inflammatory disease, involves the skin in about 25% of patients. The most common lesions are erythema nodosum, plaques, maculopapular eruptions, subcutaneous nodules, and lupus pernio. Treatment is not required, since the lesions usually resolve spontaneously in two to four weeks.
Subcutaneous emphysema is also considered a hallmark of Fournier gangrene. [26] Symptoms of subcutaneous emphysema can result when infectious organisms produce gas by fermentation. When emphysema occurs due to infection, signs that the infection is systemic (i.e. that it has spread beyond the initial location) are also present. [9] [21]
Centrilobular emphysema, also called centriacinar emphysema, affects the centre of a pulmonary lobule (centrilobular) in the lung, the area around the terminal bronchiole and the first respiratory bronchiole, and can be seen on imaging as an area around the tip of the visible pulmonary artery.
Pulmonary interstitial emphysema (PIE) is a collection of air outside of the normal air space of the pulmonary alveoli, found instead inside the connective tissue of the peribronchovascular sheaths, interlobular septa, and visceral pleura. (This supportive tissue is called the pulmonary interstitium.)
Hypersensitivity Pneumonitis; Other names: Allergic alveolitis, bagpipe lung, extrinsic allergic alveolitis (EAA) High magnification photomicrograph of a lung biopsy taken showing chronic hypersensitivity pneumonitis (), showing mild thickening of the walls of the small air sacs by invasion of white blood cells.
Low magnification micrograph of pneumatosis intestinalis in bowel wall.. Pneumoperitoneum (or peritoneal emphysema), air or gas in the abdominal cavity.The most common cause is a perforated abdominal viscus, generally a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma.
Sarcoidosis involves the skin in between 9 and 37% of cases and is more common in African Americans than in European Americans. [28] The skin is the second-most commonly affected organ after the lungs. [ 33 ]
A diver with symptoms of mediastinal emphysema may also have any combination of arterial gas embolism, pneumothorax and subcutaneous or pulmonary interstitial emphysema. Factors which may prevent free escape of the compressed breathing gas include holding the breath or respiratory obstructions such as cysts, mucus plugs, or scar tissue. [10]