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4-Formylphenyl boronic acid crystallizes in colorless needles [1] or is obtained as an odorless, whitish powder, which dissolves little in cold but better in hot water. The compound is quite stable [3] and readily forms dimers and cyclic trimeric anhydrides, which complicate purification and tend to protodeboronize, a secondary reaction that occurs frequently in the Suzuki coupling, with ...
Phenylboronic acid or benzeneboronic acid, abbreviated as PhB(OH) 2 where Ph is the phenyl group C 6 H 5 - and B(OH) 2 is a boronic acid containing a phenyl substituent and two hydroxyl groups attached to boron. Phenylboronic acid is a white powder and is commonly used in organic synthesis.
4-Fluorophenibut (developmental code name CGP-11130; also known as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABA B receptor agonist which was never marketed. [1] It is selective for the GABA B receptor over the GABA A receptor ( IC 50 = 1.70 μM and > 100 μM, respectively). [ 1 ]
Fluoroboric acid is the principal precursor to fluoroborate salts, which are typically prepared by treating the metal oxides with fluoroboric acid. The inorganic salts are intermediates in the manufacture of flame-retardant materials and glazing frits, and in electrolytic generation of boron. H[BF 4] is also used in aluminum etching and acid ...
[161] [162] [164] [165] Among 31 human newborns exposed to spironolactone in the first trimester, there were no signs of any specific birth defects. [165] A case report described a woman who was prescribed spironolactone during pregnancy with triplets and delivered all three (one boy and two girls) healthy; there was no feminization in the boy ...
Phenibut is used in Russia, Ukraine, Belarus and Latvia as a pharmaceutical drug to treat anxiety and to improve sleep (e.g., in the treatment of insomnia). [5] [6] It is also used for various other indications, including the treatment of asthenia, depression, alcoholism, alcohol withdrawal syndrome, post-traumatic stress disorder, stuttering, tics, vestibular disorders, Ménière's disease ...
1-Aminocyclopropanecarboxylic acid: 22059-21-8 C 4 H 7 NO 3: aceturic acid: C 4 H 7 NO 4: aspartic acid Asp: 56-84-8 C 4 H 8: cyclobutane: 287-23-0 C 4 H 8 N 2 O 3: asparagine Asn: 70-47-3 C 4 H 8 O: tetrahydrofuran THF: 109-99-9 C 4 H 8 O 2: ethyl acetate: C 4 H 8 O 3: gamma-Hydroxybutyric acid: 591-81-1 C 4 H 9 ClHg n-Butylmercuric chloride ...
The mechanism of organotrifluoroborate-based Suzuki-Miyaura coupling reactions has recently been investigated in detail. The organotrifluoroborate hydrolyses to the corresponding boronic acid in situ, so a boronic acid can be used in place of an organotrifluoroborate, as long as it is added slowly and carefully. [7] [8]