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Hence, an initial stimulus can trigger the expression of a large number of genes, leading to physiological events like the increased uptake of glucose from the blood stream [50] and the migration of neutrophils to sites of infection. The set of genes and their activation order to certain stimuli is referred to as a genetic program. [51]
In Kamin's blocking effect [1] the conditioning of an association between two stimuli, a conditioned stimulus (CS) and an unconditioned stimulus (US) is impaired if, during the conditioning process, the CS is presented together with a second CS that has already been associated with the unconditioned stimulus.
The dual perception of the stimulus produces an interaction that facilitates association of the experience through an additive neural response and memorization of the stimulus. This association can also be made between olfactory and tactile stimuli during the act of swallowing. In each case, temporal synchrony is important. [28]
The connection between the external stimulus to the spiking probability is made in two steps: First, a receptor cell model translates the raw external stimulus to neurotransmitter concentration, and then, a spiking neuron model connects neurotransmitter concentration to the firing rate (spiking probability).
Autocrine signaling occurs when the chemical signal acts on the same cell that produced the signaling chemical. [1] Intracrine signaling occurs when the chemical signal produced by a cell acts on receptors located in the cytoplasm or nucleus of the same cell. [2] Juxtacrine signaling occurs between physically adjacent cells. [3]
Differential threshold or just noticeable difference (JDS) is the smallest detectable difference between two stimuli, or the smallest difference in stimuli that can be judged to be different from each other. [8] Weber's Law is an empirical law that states that the difference threshold is a constant fraction of the comparison stimulus. [8]
The receptors which react to the stimulus and initiate the process of sensation are commonly characterized in four distinct categories: chemoreceptors, photoreceptors, mechanoreceptors, and thermoreceptors. All receptors receive distinct physical stimuli and transduce the signal into an electrical action potential.
Stimulus filtering occurs when an animal's nervous system fails to respond to stimuli that would otherwise cause a reaction to occur. [1] The nervous system has developed the capability to perceive and distinguish between minute differences in stimuli, which allows the animal to only react to significant impetus. [ 2 ]