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Cardiopulmonary bypass (CPB) or heart-lung machine, also called the pump or CPB pump, is a machine that temporarily takes over the function of the heart and lungs during open-heart surgery by maintaining the circulation of blood and oxygen throughout the body. [1] As such it is an extracorporeal device. CPB is operated by a perfusionist. The ...
Postperfusion syndrome, also known as "pumphead", is a constellation of neurocognitive impairments attributed to cardiopulmonary bypass (CPB) during cardiac surgery. Symptoms of postperfusion syndrome are subtle and include defects associated with attention, concentration, short-term memory, fine motor function, and speed of mental and motor ...
It was developed by heart surgeon Dr. Michael DeBakey [4] for blood transfusions [5] while he was a medical student in 1932 and later used by him for cardiopulmonary bypass [6] systems. A specialized nonocclusive roller pump (US Patent 5222880) [7] using soft flat tubing was developed in 1992 for cardiopulmonary bypass systems.
Generally, it is used either post-cardiopulmonary bypass or in late-stage treatment of a person with profound heart and/or lung failure, although it is now seeing use as a treatment for cardiac arrest in certain centers, allowing treatment of the underlying cause of arrest while circulation and oxygenation are supported.
Another purse string is placed in the right atrium for the venous cannula. Once the cannulas and the catheter are placed, cardiopulmonary bypass (CPB) is commenced. Deoxygenated blood arriving to the heart from veins is forwarded to the CPB machine to get oxygenated, then delivered to the aorta to keep the rest of the body saturated.
Cardiopulmonary bypass (CPB) is a medical technique to oxygenate the blood and remove the carbon dioxide during the cardiac operation. [4] It can be seen as a “pump” to serve as a heart-lung machine whose function is sustaining blood circulatory and transporting oxygen to red blood cells before blood is flowing backwards the arterial ...
Impella was approved for mechanical circulatory support in 2008, but large-scale, real-world data on its use are lacking. In June 2008, the Impella 2.5 heart pump received FDA 510(k) clearance [22] for partial circulatory support for periods of up to six hours during cardiac procedures not requiring cardiopulmonary bypass.
A phase 1 clinical trial is underway (as of August 2009), consisting of patients with coronary artery bypass grafting and patients in end-stage heart failure who have a left ventricular assist device. The trial involves testing a patch called Anginera which contains cells that secrete hormone-like growth factors stimulating other cells to grow.
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