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For women, there may also be a yellow-green, itchy, frothy, foul-smelling ("fishy" smell) vaginal discharge. In rare cases, lower abdominal pain can occur. Symptoms usually appear within 5 to 28 days of exposure. [7] Sometimes trichomoniasis can be confused with chlamydia because the symptoms are similar. [8]
Trichomonas vaginalis from a vaginal swab. This is a heavy infection; there were probably thousands of trichomonads in the vagina. Alfred Francois Donné (1801–1878) was the first to describe a procedure to diagnose trichomoniasis through "the microscopic observation of motile protozoa in vaginal or cervical secretions" in 1836.
The first effective treatment for a sexually transmitted infection was salvarsan, a treatment for syphilis. With the discovery of antibiotics , a large number of sexually transmitted infections became easily curable, and this, combined with effective public health campaigns against STIs, led to a public perception during the 1960s and 1970s ...
“The most common cause of vaginal odor is an imbalance in the normal flora in the vagina,” which causes a fishy odor, irritation, and thin to no vaginal discharge, says Dr. Streicher.
[13] [14] Genetic deficiencies of the FMO3 enzyme cause primary trimethylaminuria, also known as "fish odor syndrome". [ 8 ] [ 15 ] FMO3 is also involved in the metabolism of many xenobiotics (i.e., exogenous compounds which are not normally present in the body), [ 9 ] [ 10 ] such as the oxidative deamination of amphetamine .
G. vaginalis is associated with bacterial vaginosis, [17] which may be asymptomatic, [18] or may have symptoms including vaginal discharge, vaginal irritation, and a "fish-like" odor. In the amine whiff test , 10% KOH is added to the discharge; a positive result is indicated if a fishy smell is produced.