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Around one in 100 people in the general US population is a carrier for type I Gaucher's disease, giving a prevalence of one in 40,000. [40] Among Ashkenazi Jews, the rate of carriers is considerably higher, at roughly one in 15. [40] Type II Gaucher's disease shows no particular preference for any ethnic group. [citation needed]
Eliglustat, sold under the brand name Cerdelga, is a medication used for the treatment of Gaucher's disease. It was discovered at the University of Michigan, developed by Genzyme Corp, and was approved by the FDA in August 2014. [7] Commonly used as the tartrate salt, the compound is believed to work by inhibition of glucosylceramide synthase.
The addition of zinc in the diet aids in the development of collagen and wound healing, and also will prevent the skin from becoming dry and flaky. [27] Senior dogs can obtain zinc in their diet through the addition of various ingredients, including; red meats, whole grains, poultry by-product meals, and fish meals.
In this treatment, the accumulated compounds are inhibited from forming in the body of a patient with a lysosomal storage disease. [10] The accumulated compounds are responsible for the symptoms of these disorders, and they form via a multi-step biological pathway. [ 10 ]
Hypoallergenic diets for dogs with food allergies consist of either limited ingredients, [86] novel proteins, [83] or hydrolyzed proteins. [87] Limited ingredients make it possible to identify the suspected allergens causing these allergic reactions, as well as making it easy to avoid multiple ingredients if a canine is allergic to more than ...
The lethal dose for 50% of dogs is 100 – 200 mg per kilogram (kg) of body weight, yet some dogs will exhibit signs of toxicosis after ingesting as little as 20 mg per kg. [38] In case of accidental intake of chocolate, especially involving a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended ...
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