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  2. The best muscle pain relief creams of 2025, according to ...

    www.aol.com/lifestyle/best-muscle-pain-relief...

    Complete with a 4.6-star rating from more than 27,700 Amazon buyers, one shopper said that the warming relief offers "long lasting relief so you can sleep and relax." Pros Goes on cool but warms up

  3. Is Acetaminophen Or Ibuprofen Better For Pain? Here's ... - AOL

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    Acetaminophen, or Tylenol, changes our perception of pain. “It’s a very safe medication to take — you can even take it during pregnancy — but it’s not necessarily addressing the ...

  4. Buspirone - Wikipedia

    en.wikipedia.org/wiki/Buspirone

    Buspirone has also been found to bind with much higher affinity to the dopamine D 3 and D 4 receptors, where it is similarly an antagonist. [45] A major metabolite of buspirone, 1-(2-pyrimidinyl)piperazine (1-PP), occurs at higher circulating levels than buspirone itself and is known to act as a potent α 2-adrenergic receptor antagonist.

  5. FDA approves new type of non-opioid pain medication, 1st of ...

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    This is the first class of non-opioid pain medication approved to treat moderate to severe acute pain approved by the FDA in more than 20 years. ... Opioids are no better than a placebo for back ...

  6. Azapirone - Wikipedia

    en.wikipedia.org/wiki/Azapirone

    Buspirone was originally classified as an azaspirodecanedione, shortened to azapirone or azaspirone due to the fact that its chemical structure contained this moiety, and other drugs with similar structures were labeled as such as well. However, despite all being called azapirones, not all of them actually contain the azapirodecanedione ...

  7. Suzetrigine - Wikipedia

    en.wikipedia.org/wiki/Suzetrigine

    Suzetrigine, sold under the brand name Journavx, is a medication used for the management of pain. [1] [2] It is a non-opioid, small-molecule analgesic that works as a selective inhibitor of Na v 1.8-dependent pain-signaling pathways in the peripheral nervous system, [3] [4] avoiding the addictive potential of opioids.