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The most common form of sterilization in dogs and cats is surgical, spaying in females and castration in males. Non-surgical fertility control can either result in sterilization or temporary contraception and could offer a cheaper way to keep wild dog and cat populations under control. As of 2019, only contraceptives are commercially available.
Pyometra is a result of hormonal and structural changes in the uterus lining. This can happen at any age, regardless of how many heat cycles have occurred or previous pregnancies (or lack thereof), although it becomes more common as the dog gets older. The main risk period for a female is for eight weeks after her peak standing heat has ended. [2]
The incidence of mammary tumours in un-spayed female dogs is 71% (of which approximately 50% will be malignant and 50% will be benign), but if a dog is spayed before its first heat cycle, the risk of developing a mammary tumour is reduced to 0.35%—a 99.5% reduction.
Research in the 1960s proved that female animals permitted to reach sexual maturity prior to being spayed were susceptible to a higher risk of mammary cancer than those animals spayed prior to their first cycle. As a result, the recommendation was revised to perform surgeries just prior to the average anticipated age for the first cycle, 4 to 6 ...
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Female cats and dogs are seven times more likely to develop mammary tumors if they are not spayed before their first heat cycle. [77] The high dietary estrogen content of the average commercial pet food may be contributing factors in the development of mammary cancer, especially when these exogenous sources are added to those normal estrogens ...