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The last decade of studies on Modic changes have shown that Modic changes are associated with many treatment-resistant pain episodes and may result in patients entering a state of chronic low back pain. On average, individuals with Modic changes have had chronic pain for longer than individuals suffering from non-Modic changes back pain. [9] [10]
Spinal stenosis began to be recognized as an impairing condition in the 1950s and 1970s. Individuals who experience back pain and other symptoms are likely to have bigger spinal canals than those who are asymptomatic. [45] A normal-sized lumbar canal is rarely encountered in persons with either disc disease or those requiring a laminectomy. [31]
Spinal stenosis is an abnormal narrowing of the spinal canal or neural foramen that results in pressure on the spinal cord or nerve roots. [6] Symptoms may include pain, numbness , or weakness in the arms or legs. [ 1 ]
Low back pain or lumbago is a common disorder involving the muscles, nerves, and bones of the back, in between the lower edge of the ribs and the lower fold of the buttocks. Pain can vary from a dull constant ache to a sudden sharp feeling. [4]
Symptoms for spinal tumors may vary due to factors such as the type of tumor, the region of the spine, and the health of the patient. Back pain is the most common symptom and it can be a problem if the pain is severe, has a time frame that lasts longer than it would for a normal injury, and becomes worse while laying down or at rest.
Spondylolysis is a common cause of low back pain in preadolescents and adolescent athletes, as it accounts for about 50% of all low back pain. [7] It is believed that both repetitive trauma and an inherent genetic weakness can make an individual more susceptible to spondylolysis.
The inflammatory mediators of RA including cytokines, growth factors, metalloproteinases destroy articular cartilage, subchondral bone, tendons and ligaments.Destructive synovitis leads to bone erosion and causes the ligaments of the spine to become too laxed (loose), eventually resulting in cervical spinal instability (loose neck bones).
Bertolotti's syndrome is a commonly missed cause of back pain which occurs due to lumbosacral transitional vertebrae (LSTV). It is a congenital condition but is not usually symptomatic until one's later twenties or early thirties. [1] However, there are a few cases of Bertolotti's that become symptomatic at a much earlier age.