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In areas with triatomine bugs, transmission of T. cruzi can be prevented by sleeping under bed nets and by housing improvements that prevent triatomine bugs from colonizing houses. [16] Blood transfusion was formerly the second-most common mode of transmission for Chagas disease. [35]
Trypanosomiasis could, in future be prevented by genetically altering the tsetse fly. As the tsetse fly is the main vector of transmission, making the fly immune to the disease by altering its genome could be the main component in an effort to eradicate the disease.
Trypanosoma Cruz causes Chagas disease, and there are efforts to use paratransgenesis to prevent the spread of this disease. The strategy is to alter the microbe then reinsert it into the insect that has been genetically modified to alter pathogens.
Chagas is a potentially fatal neglected disease that affects between 8 and 13 million people worldwide. DNDi's Time to Treat campaign is pushing for increased political interest in new treatments for Chagas disease, increased public awareness of the disease and treatment limitations and increased public and private investment in R&D.
Chagas Disease is spread when an infected triatomine defecates on or near a host, causing the parasite to enter the body of the host, usually through the site of a wound. [2] This is usually how T. cruzi is transmitted, but it can also occur during blood transfusion, organ donation or the consumption of contaminated food or drink. [2]
Chagas disease undergoes two phases, which are the acute and the chronic phase. The acute phase can last from two weeks to two months but can go unnoticed because symptoms are minor and short-lived. Symptoms of the acute phase include swelling, fever, fatigue, and diarrhea.
Chagas disease is caused by Trypanosoma cruzi and is mostly spread by Triatominae. It is endemic to 21 countries in Latin America. There are over 30,000 new cases per year and 12,000 deaths due to the disease. [143] Eradication efforts focus on the elimination of vector-borne transmission and the elimination of the vectors themselves. [143]
Acute Chagas disease can be treated using benznidazole or nifurtimox. Chronic chagas disease is asymptomatic and causes heart and gastrointestinal cells to be affected. Currently, there are only investigational treatments for this disease. Unfortunately, vaccines are not effective with Chagas disease due to antigenic variation. This pathogen ...