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  2. Trough level - Wikipedia

    en.wikipedia.org/wiki/Trough_level

    In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. [3] A trough level is contrasted with a "peak level" ( C max ), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time.

  3. Relative biological effectiveness - Wikipedia

    en.wikipedia.org/wiki/Relative_biological...

    For such purposes, doses should be evaluated in terms of absorbed dose (in gray, Gy), and where high-LET radiations (e.g., neutrons or alpha particles) are involved, an absorbed dose, weighted with an appropriate RBE, should be used" Radiation weighting factors are largely based on the RBE of radiation for stochastic health risks. However, for ...

  4. Committed dose equivalent - Wikipedia

    en.wikipedia.org/wiki/Committed_dose_equivalent

    CDE is defined by the United States Nuclear Regulatory Commission in Title 10, Section 20.1003, of the Code of Federal Regulations (10 CFR 20.1003), such that "The Committed dose equivalent, CDE (H T,50) is the dose to some specific organ or tissue of reference (T) that will be received from an intake of radioactive material by an individual during the 50-year period following the intake".

  5. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  6. Infliximab - Wikipedia

    en.wikipedia.org/wiki/Infliximab

    Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases. This includes Crohn's disease , ulcerative colitis , rheumatoid arthritis , ankylosing spondylitis , psoriasis , psoriatic arthritis , and Behçet's disease . [ 23 ]

  7. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...

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