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Pacinian corpuscles are rapidly adapting phasic receptors that detect gross pressure changes and vibrations in the skin. [6] Pacinian corpuscles have a large receptive field on the skin's surface with an especially sensitive center. [7] The corpuscles are especially sensitive to vibrations, which they can sense even centimeters away. [7]
With improved histological techniques, a second touch receptor type, Merkel cell-neurite complexes, was found in the stratum germinativum at the bottom of the epidermis, and a third, lamellated corpuscles of Vater and Pacini, was discovered in the stratum papillare of the dermis underneath the Merkel cells as published by Halata in 1975.
Tactile corpuscles or Meissner's corpuscles are a type of mechanoreceptor discovered by anatomist Georg Meissner (1829–1905) and Rudolf Wagner. [ 1 ] [ 2 ] This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to pressure .
Red arrows indicate secreted lamellar bodies, and green arrows indicate lamellar bodies in the cytoplasm. Scale bar = 200 nm. In cell biology, lamellar bodies (otherwise known as lamellar granules, membrane-coating granules (MCGs), keratinosomes or Odland bodies) are secretory organelles found in type II alveolar cells in the lungs, and in keratinocytes in the skin.
Merkel cell. Merkel cells are found in the skin and some parts of the mucosa of all vertebrates. In mammalian skin, they are clear cells found in the stratum basale [2] [3] (at the bottom of sweat duct ridges) of the epidermis approximately 10 μm in diameter.
The bulbous corpuscle, Ruffini ending or Ruffini corpuscle is a slowly adapting mechanoreceptor located in the cutaneous tissue between the dermal papillae and the hypodermis. It is named after Angelo Ruffini .
A lamella (pl.: lamellae) in biology refers to a thin layer, membrane or plate of tissue. [1] This is a very broad definition, and can refer to many different structures. Any thin layer of organic tissue can be called a lamella and there is a wide array of functions an individual layer can serve.
The dorsal column–medial lemniscus pathway (DCML) (also known as the posterior column-medial lemniscus pathway (PCML) is the major sensory pathway of the central nervous system that conveys sensations of fine touch, vibration, two-point discrimination, and proprioception (body position) from the skin and joints.