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Metronidazole and its metabolites are mainly excreted via the kidneys (77%) and to a lesser extent via the faeces (14%). [7] [8] The biological half-life of metronidazole in healthy adults is eight hours, in infants during the first two months of their lives about 23 hours, and in premature babies up to 100 hours. [61]
The metronidazole tablet may have an unpleasant metallic taste, deteriorating drug compliance. [47] This medication may also induce rare side effect in the central nervous system, including neurotoxicity ( encephalopathy , peripheral neuropathy , seizure ).
1st week: PPI (standard dose) and amoxicillin 1 g bid 2nd week: PPI (standard dose), amoxicillin 1 g, metronidazole 0.5 g and clarithromycin 0.5 g bid First line therapy Bismuth-containing quadruple therapy 10–14 PPI (standard dose) bid, tetracycline 0.5 g qid, metronidazole 0.25 g qid and bismuth standard dose qid First line or second line ...
Possible side effects [4] Mechanism of action Aminoglycosides; Amikacin: Amikin: Infections caused by Gram-negative bacteria, such as Escherichia coli and Klebsiella particularly Pseudomonas aeruginosa. Effective against aerobic bacteria (not obligate/facultative anaerobes) and tularemia. All aminoglycosides are ineffective when taken orally as ...
Allergic rashes, like a drug rash, occur when you ingest an allergen, including certain foods, ... although many adults also have eczema-prone skin. ... including metronidazole, erythromycin, and ...
Therefore, potential risks of side effects and effectiveness depend on the type of antibiotic administered. [ 63 ] Antibiotics such as metronidazole , tinidazole , cephamandole , latamoxef , cefoperazone , cefmenoxime , and furazolidone , cause a disulfiram -like chemical reaction with alcohol by inhibiting its breakdown by acetaldehyde ...
There have been many antibiotic regimes proposed for the treatment of AgP. However, the combination of choice according to current research is a combination of amoxicillin (500 mg, thrice/day) and metronidazole (200 mg, thrice/day), for 7 days, starting on the day of the final debridement.
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