Ads
related to: average dose of spironolactone for hirsutism treatment in patients
Search results
Results From The WOW.Com Content Network
Spironolactone is commonly used in the treatment of hirsutism in women, and is considered to be a first-line antiandrogen for this indication. [68] Spironolactone can be used in the treatment of female-pattern hair loss (pattern scalp hair loss in women). [69] There is tentative low quality evidence supporting its use for this indication. [70]
Spironolactone has been found to be effective in the treatment of hirsutism in women at a dosage of as low as 50 mg/day. [60] At dosages of 100 mg/day and 200 mg/day, observed reductions in hair shaft diameter were 19% ± 8% and 30% ± 3%, respectively (p = 0.07).
[3] [23] Since dutasteride is an inhibitor of both type 1 and 2 5α-reductases, it could theoretically be a more effective therapy for hirsutism. However, dutasteride is not recommended for this indication due to a lack of supportive clinical evidence and a substantial risk of birth defects in female patients who inadvertently become pregnant ...
For premium support please call: 800-290-4726 more ways to reach us more ways to reach us
For those with signs of hyperandrogenism (excessive androgen hormones) and other hormonal imbalances, spironolactone may be an effective treatment for female pattern hair loss.
Unlike spironolactone, bicalutamide has no antimineralocorticoid activity, [97] and for this reason, has no risk of hyperkalemia (which can, rarely/in severe cases, result in hospitalization or death) [112] or other antimineralocorticoid side effects such as urinary frequency, dehydration, hypotension, hyponatremia, metabolic acidosis, or ...
Hirsutism and acne both respond well to the hormonal treatments described above, with 60–100% of patients reporting an improvement in hirsutism. [65] Androgenic alopecia however, does not show an improvement with hormonal treatments and requires other treatments, such as hair transplantation .
[14] [35] Like spironolactone, flutamide is typically only used by women. [36] Bicalutamide is another option for the treatment of female pattern hair loss. [37] [38] [39] It has a far lower risk of liver toxicity than flutamide and is said to have an excellent safety profile.