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Side effects can include fatigue, anemia, muscle aches, fever, and/or swelling in the feet or legs. Flu-like symptoms are common after the first infusion, although not subsequent infusions, and are thought to occur because of its potential to activate human gamma delta T cell (γδ T cells).
Common side effects include bone pain, low calcium levels, nausea, and dizziness. Osteonecrosis of the jaw is a rare complication which has been associated with the use of bisphosphonates, including pamidronate. [3] Pamidronate activates human γδ T cells in vitro and in vivo, which may lead to flu-like symptoms upon administration.
Intraosseous infusion (into the bone marrow) is, in effect, an indirect intravenous access because the bone marrow drains directly into the venous system. This route is occasionally used for drugs and fluids in emergency medicine and pediatrics when intravenous access is difficult.
Erythropoiesis-stimulating agents (ESA) are medications which stimulate the bone marrow to make red blood cells. [1] They are used to treat anemia due to end stage kidney disease, chemotherapy, major surgery, or certain treatments in HIV/AIDS. [1] [2] In these situations they decrease the need for blood transfusions. [2]
Common side effects include bone marrow suppression, liver and kidney problems, nausea, fever, rash, shortness of breath, mouth sores, diarrhea, neuropathy, and hair loss. [3] Use during pregnancy will likely result in fetal harm. [3] Gemcitabine is in the nucleoside analog family of medication. [3]
[15] [18] [19] [20] A 2017 Cochrane review found that for people with early breast cancer, bisphosphonate treatment may reduce the risk of the cancer spreading to the person's bone, however, for people who had advanced breast cancer bisphosphonate treatment did not appear to reduce the risk of the cancer spreading to the bone. [15] Side effects ...
Common side effects include bone marrow suppression, vomiting, diarrhea, liver problems, rash, ulcer formation in the mouth, and bleeding. [2] Other serious side effects include loss of consciousness, lung disease, and allergic reactions. [2] Use during pregnancy may harm the baby. [2]
Common side effects (1 to 10% of patients) include constipation, abdominal pain, nausea, and acid reflux. [4] Use is not recommended during pregnancy or in those with poor kidney function. [5] Alendronic acid works by decreasing the activity of cells that break down bone. [4]