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Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer ...
CIPN afflicts between 30% and 40% of patients undergoing chemotherapy. Antineoplastic agents in chemotherapy are designed to eliminate rapidly dividing cancer cells, but they can also damage healthy structures, including the peripheral nervous system. [1] CIPN involves various symptoms such as tingling, pain, and numbness in the hands and feet. [2]
Molly Smith experienced pins and needles in her hands and feet, which eventually led to the discovery of a cyst and a diagnosis of ovarian cancer. As a summer camp volunteer in 2022, Molly Smith ...
Typical signs of acral lentiginous melanoma include the following [1] Irregular area of pigmentation (usually dark brown or black) found on the palms, feet, or under the nail; Longitudinal tan, black, or brown streak on a nail; Pigmentation of proximal nail fold; Other uncommon presentations can include:
Weakness or numbness in the legs or feet. Fatigue. Unintentional weight loss “Prostate cancer tends to spread to the bones, which can be painful, cause fractures, and limit mobility,” Dr ...
difficulty moving feet in contact with floor, tendency to fall backwards Bruns nystagmus: Ludwig Bruns: neurology: cerebellopontine angle tumor, vestibular schwannoma: nystagmus that coarsens in amplitude on lateral gaze Brushfield spots: Thomas Brushfield: ophthalmology, genetics: Downs' syndrome or non-pathological: greyish-white spots at ...
Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. [3] [4] Cancer can be difficult to diagnose because its signs and symptoms are often nonspecific, meaning they may be general phenomena that do not point directly to a specific disease process. [5]
RS3PE has been documented in patients with cancers (Non-Hodgkin's lymphoma, gastric cancer, pancreatic cancer, lung cancer, breast cancer, colon cancer, prostate cancer and bladder cancer, among others), in whom it might represent a paraneoplastic manifestation. [10] [11] [12] Other underlying disorders include vasculitides such as ...