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The mammillary bodies also mamillary bodies, are a pair of small round brainstem nuclei. [2] They are located on the undersurface of the brain that, as part of the diencephalon, form part of the limbic system. They are located at the ends of the anterior arches of the fornix. [3]
The mammillary bodies directly or indirectly connect to the amygdala, hippocampus, and thalami as major structures in the limbic system. [6] The mammillothalamic tract carries signals from the mammillary bodies via the anterior thalamus to support spatial memory. [3] [4]
Its various components support a variety of functions including emotion, behavior, long-term memory, and olfaction. [ 2 ] The limbic system is involved in lower order emotional processing of input from sensory systems and consists of the amygdala , mammillary bodies , stria medullaris , central gray and dorsal and ventral nuclei of Gudden. [ 3 ]
The mammillary bodies are two clusters of cell bodies found at the ends of the posterior fibres of the fornix within the diencephalon. The mammillary bodies relay information from the hippocampal formation (via the fornix) to the thalamus (via the mammillothalamic tract). The mammillary bodies are integral parts of the limbic system and have ...
The mammillary bodies are an important part of the Papez circuit. If there is damage, such as loss of neurons and/or myelination, to the mammillary bodies, the Papez circuit can be severely affected. There will be a disruption in the connecting parts of the system.
Anatomical "lines", or "reference lines," are theoretical lines drawn through anatomical structures and are used to describe anatomical location. The following reference lines are identified in Terminologia Anatomica: Anterior median line; Lateral sternal line: A vertical line corresponding to the lateral margin of the sternum.
The mammillary bodies form the floor posterior of the tuber cinereum, acting as the link between the fornix and the hypothalamus. Posterior of the mamillary bodies, the ventricle becomes the opening of the cerebral aqueduct, the inferior borders becoming the crus cerebri (sometimes historically called the cerebral peduncle) of the midbrain.
The mammillotegmental fasciculus (mammillotegmental tract, or mammillotegmental bundle of Gudden) is a small bundle of efferent fibers from the hypothalamus running from the mammillary body to the tegmentum. [1] Its functions are not well defined for humans, but based on animal studies it seems to be related to regulating visceral function and ...