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Diphenhydramine is a potent antimuscarinic (a competitive antagonist of muscarinic acetylcholine receptors) and, as such, at high doses can cause anticholinergic syndrome. [69] The utility of diphenhydramine as an antiparkinson agent is the result of its blocking properties on the muscarinic acetylcholine receptors in the brain.
Cognitive function decline (Confusion, memory loss and difficulty in concentration) [18] paralysis, Tachycardia, [19] Hypotension (Anticholinergics are histamine-inducing, leading to vasodilation during anaphylactic reaction, hence a dropping in blood pressure), [20] constipation, dry mouth, dry eyes, hypohidrosis/ anhidrosis, blurry vision, or ...
Mydriasis can be induced via modulation of adrenergic or cholinergic signalling. Drugs that can cause mydriasis include: Stimulants (typically monoaminergics) such as amphetamines, cocaine, MDMA, and mephedrone. Anticholinergics such as diphenhydramine, atropine, hyoscyamine, and scopolamine antagonize the muscarinic acetylcholine receptors in
Suddenly having dry eyes is likely related to an environmental trigger, although an underlying medical condition is also possible. Find answers here. What Causes Dry Eyes All of a Sudden Without a ...
The best eye drops for dry eyes in 2023 work to soothe various dry eye symptoms. Here, find expert-approved picks from Refresh, Systane, Opti-Free, and more.
Dry eye syndrome can lead to blurred vision, instability of the tear film, increased risk of damage to the ocular surface such as scarring of the cornea, and changes in the eye including the neurosensory system. [2] [6] Dry eye occurs when either the eye does not produce enough tears or when the tears evaporate too quickly. [2]