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  2. International unit - Wikipedia

    en.wikipedia.org/wiki/International_unit

    In pharmacology, the international unit (IU) is a unit of measurement for the effect or biological activity of a substance, for the purpose of easier comparison across similar forms of substances. International units are used to quantify vitamins and biologics ( hormones , some medications , vaccines , blood products and similar biologically ...

  3. Calcifediol - Wikipedia

    en.wikipedia.org/wiki/Calcifediol

    Calcifediol is the precursor for calcitriol, the active form of vitamin D. [3] [4] It is synthesized in the liver, by hydroxylation of cholecalciferol (vitamin D 3) at the 25-position. [3] This enzymatic 25-hydroxylase reaction is mostly due to the actions of CYP2R1 , present in microsomes , although other enzymes such as mitochondrial CYP27A1 ...

  4. Cholecalciferol - Wikipedia

    en.wikipedia.org/wiki/Cholecalciferol

    The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...

  5. Vitamin D deficiency - Wikipedia

    en.wikipedia.org/wiki/Vitamin_D_deficiency

    Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.

  6. List of conversion factors - Wikipedia

    en.wikipedia.org/wiki/List_of_conversion_factors

    Relation to SI units barrel of oil equivalent: boe ≈ 5.8 × 10 6 BTU 59 °F: ≈ 6.12 × 10 9 J: British thermal unit (ISO) BTU ISO: ≡ 1.0545 × 10 3 J = 1.0545 × 10 3 J: British thermal unit (International Table) BTU IT = 1.055 055 852 62 × 10 3 J: British thermal unit (mean) BTU mean: ≈ 1.055 87 × 10 3 J: British thermal unit ...

  7. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  8. Calcium/cholecalciferol - Wikipedia

    en.wikipedia.org/wiki/Calcium/Cholecalciferol

    Calcium/cholecalciferol is a combination of a calcium salt and vitamin D 3 (cholecalciferol). It is used to prevent and treat lack of calcium and vitamin D in the elderly, as well for osteoporosis in combination with other medications. [1] [2]

  9. CYP2R1 - Wikipedia

    en.wikipedia.org/wiki/CYP2R1

    The conversion of vitamin D, especially cholecalciferol, to 25(OH)D (calcifediol) is one of the key steps in the vitamin D hormonal system. The CYP2R1 enzymatic activity achieving this process was previously thought to be constitutively expressed and stable, so that serum 25(OH)D was a measure of the supply of vitamin D. [9]

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