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  2. Citicoline - Wikipedia

    en.wikipedia.org/wiki/Citicoline

    Citicoline , also known as cytidine diphosphate-choline (CDP-choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes. Citicoline is naturally occurring in the cells of human and animal tissue, in particular the organs.

  3. Phosphatidylcholine - Wikipedia

    en.wikipedia.org/wiki/Phosphatidylcholine

    Although multiple pathways exist for the biosynthesis of phosphatidylcholine, the predominant route in eukaryotes involves condensation between diacylglycerol (DAG) and cytidine 5'-diphosphocholine (CDP-choline or citicoline). The conversion is mediated by the enzyme diacylglycerol cholinephosphotransferase.

  4. Choline-phosphate cytidylyltransferase - Wikipedia

    en.wikipedia.org/wiki/Choline-phosphate_cytidyly...

    Choline-phosphate cytidylyltransferase (EC 2.7.7.15) is an enzyme that catalyzes the chemical reaction CTP + choline phosphate ⇌ {\displaystyle \rightleftharpoons } diphosphate + CDP-choline where the two substrates of this enzyme are CTP and choline phosphate , and the two products are diphosphate and CDP-choline .

  5. Phosphatidylcholine synthase - Wikipedia

    en.wikipedia.org/wiki/Phosphatidylcholine_synthase

    In enzymology, a phosphatidylcholine synthase (EC 2.7.8.24) is an enzyme that catalyzes the chemical reaction. CDP-diacylglycerol + choline CMP + phosphatidylcholine. Thus, the two substrates of this enzyme are CDP-diacylglycerol and choline, whereas its two products are CMP and phosphatidylcholine.

  6. Choline - Wikipedia

    en.wikipedia.org/wiki/Choline

    Choline is a quaternary ammonium cation.The cholines are a family of water-soluble quaternary ammonium compounds. [2] Choline is the parent compound of the cholines class, consisting of ethanolamine residue having three methyl groups attached to the same nitrogen atom.

  7. Cytidine diphosphate - Wikipedia

    en.wikipedia.org/wiki/Cytidine_diphosphate

    Cytidine diphosphate, abbreviated CDP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside cytidine. CDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase cytosine. In Bacillus subtilis and Staphylococcus aureus, CDP-activated glycerol and ribitol are necessary to build wall ...

  8. Mn2+-dependent ADP-ribose/CDP-alcohol diphosphatase

    en.wikipedia.org/wiki/Mn2+-dependent_ADP-ribose...

    Mn 2+-dependent ADP-ribose/CDP-alcohol diphosphatase (EC 3.6.1.53, Mn2+-dependent ADP-ribose/CDP-alcohol pyrophosphatase, ADPRibase-Mn) is an enzyme with systematic name CDP-choline phosphohydrolase. [1] [2] This enzyme catalyses the following chemical reaction (1) CDP-choline + H 2 O CMP + phosphocholine

  9. CDP-choline pathway - Wikipedia

    en.wikipedia.org/wiki/CDP-choline_pathway

    Structures and localization of the enzymes in the CDP-choline pathway. [1]: 415 The CDP-choline pathway, first identified by Eugene P. Kennedy in 1956, is the predominant mechanism by which mammalian cells synthesize phosphatidylcholine (PC) for incorporation into membranes or lipid-derived signalling molecules. [1] [2] The CDP-choline pathway ...