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  2. Azithromycin - Wikipedia

    en.wikipedia.org/wiki/Azithromycin

    Some drugs can inhibit CYP3A4, which means they reduce its activity and increase the blood levels of the drugs that depend on it for elimination. This can lead to adverse effects or drug-drug interactions. [47] Azithromycin is a member of macrolides that are a class of antibiotics with a cyclic structure with a lactone ring and sugar moieties ...

  3. Chloroquine and hydroxychloroquine during the COVID-19 ...

    en.wikipedia.org/wiki/Chloroquine_and_hydroxych...

    One such cocktail – hydroxychloroquine combined with a high dose of zinc (as a sulfate, 220 mg (50 mg elemental Zn) per day for five days, a zinc dose ~4 times higher than the reference daily intake level) [63] and an approved antibiotic, either azithromycin or doxycycline – began in May as a Phase IV trial in New York State. [65]

  4. Pharmacodynamics - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics

    The therapeutic window is the amount of a medication between the amount that gives an effect (effective dose) and the amount that gives more adverse effects than desired effects. For instance, medication with a small pharmaceutical window must be administered with care and control, e.g. by frequently measuring blood concentration of the drug ...

  5. Trimethoprim/sulfamethoxazole - Wikipedia

    en.wikipedia.org/wiki/Trimethoprim/sulfamethoxazole

    The effects of trimethoprim causes a backlog of dihydrofolate (DHF) and this backlog can work against the inhibitory effect the drug has on tetrahydrofolate biosynthesis. This is where the sulfamethoxazole comes in; its role is in depleting the excess DHF by preventing it from being synthesised in the first place.

  6. Novo Nordisk experimental obesity pill has mild-to-moderate ...

    www.aol.com/news/novo-nordisk-experimental...

    In the amycretin trial, the side effects were related to gastrointestinal discomfort, including nausea and vomiting, similar to those seen in trials of its other medicines from the same GLP-1 drug ...

  7. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

    www.aol.com/cialis-side-effects-expect-avoid...

    This side effect was most common in guys who took 10 to 20 milligrams of Cialis a day. Tadalafil Side Effects Long-Term ... But because daily-use Cialis is prescribed at a lower dosage, some side ...

  8. Quinolone antibiotic - Wikipedia

    en.wikipedia.org/wiki/Quinolone_antibiotic

    On 12 May 2016, the FDA issued a drug safety communication advising that fluoroquinolones should be reserved for these conditions only when no other options are available due to potentially permanent, disabling side effects occurring together. The drug safety communication also announced the required labeling updates to reflect this new safety ...

  9. Antimicrobial resistance - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_resistance

    The prescriber should closely adhere to the five rights of drug administration: the right patient, the right drug, the right dose, the right route, and the right time. [108] Microbiological samples should be taken for culture and sensitivity testing before treatment when indicated and treatment potentially changed based on the susceptibility ...

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