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The small number of available trials do not support the use of statins as an adjunctive therapy or as a monotherapy in multiple sclerosis. [223] A modelling study in the UK funded by the NIHR found that people aged 70 and older who take statins live longer in good health than those who do not, regardless of whether they have cardiovascular disease.
The findings show a decrease in mortality among people 60 years of age and older — including people over the age of 85 — who took statins. The study is published in Annals of Internal Medicine .
When examining the cost-effectiveness of statin use in older adults, the researchers report that statins were cost-effective, with the cost per quality-adjusted life years gained below £3,502 ...
Statins appear to be effective at preventing cardiovascular disease and death in older adults, according to new research. Most clinical trials evaluating statins have not included people 75 and ...
A risk exists of muscle damage (myopathy and rhabdomyolysis) with statins. Hypercholesterolemia is not a risk factor for mortality in persons older than 70 years and risks from statin drugs are more increased after age 85. [2] Fibrates are indicated for hypertriglyceridemia. Fibrates typically lower triglycerides by 20% to 50%.
Type 2 diabetes is observed in a small number of people, and is an uncommon class effect of all statins. [ 57 ] [ 58 ] [ 59 ] It appears it may be more likely in people who were already at a higher risk of developing diabetes before starting a statin due to multiple risk factors, for example raised fasting glucose levels. [ 60 ]