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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone, sold under the brand name Aldactone among others, is a diuretic medication primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. [4] It is also used in the treatment of high blood pressure , and low blood potassium that does not improve with supplementation , early puberty in boys, acne ...

  3. Canrenone - Wikipedia

    en.wikipedia.org/wiki/Canrenone

    Canrenone, sold under the brand names Contaren, Luvion, Phanurane, and Spiroletan, is a steroidal antimineralocorticoid [3] [4] of the spirolactone group related to spironolactone which is used as a diuretic in Europe, including in Italy and Belgium.

  4. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]

  5. Everything You Need to Know About Acne, from Causes to ... - AOL

    www.aol.com/everything-know-acne-causes...

    Spironolactone: Spironolactone is used to treat high blood pressure but is also prescribed off-label for treating acne in women. Spironolactone reduces the amount of androgen hormones in your body ...

  6. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    However, spironolactone is metabolized to three active metabolites, which give it prolonged activity (13.8 – 16. 5 hours). Spironolactone has a long half-life and is excreted 47-51% through kidneys. Patients with chronic kidney disease therefore require close monitoring when taking the drug. Spironolactone is also eliminated through feces (35-41%

  7. Overview of common vision problems and medications - AOL

    www.aol.com/overview-common-vision-problems...

    Medications for glaucoma usually come in the form of medicated eye drops. Prostaglandins (Xalatan, Travatan Z, Vyzulta): These help to relieve pressure by increasing the outflow of your aqueous ...

  8. Spirolactone - Wikipedia

    en.wikipedia.org/wiki/Spirolactone

    Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attached spiro to another ring system. The name is also used to refer to a class of synthetic steroids, called steroid-17α-spirolactones, 17α-spirolactosteroids, or simply 17α-spirolactones, which feature their spirolactone group at the C17α position.

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