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In the human genome, which, according to January 2013 estimates, has about 20,848 protein coding genes [32] in total, there are 497 nuclear genes encoding cytoplasmic tRNA molecules, and 324 tRNA-derived pseudogenes—tRNA genes thought to be no longer functional [33] (although pseudo tRNAs have been shown to be involved in antibiotic ...
The human brain contains 86 billion neurons, with 16 billion neurons in the cerebral cortex. [ 2 ] [ 1 ] Neuron counts constitute an important source of insight on the topic of neuroscience and intelligence : the question of how the evolution of a set of components and parameters (~10 11 neurons, ~10 14 synapses) of a complex system leads to ...
Regulatory RNAs Type Abbr. Function Distribution Ref. Antisense RNA: aRNA, asRNA: Transcriptional attenuation / mRNA degradation / mRNA stabilisation / Translation block
This process takes many years and is associated with some aging processes involved in oxygen-dependent tissues such as brain, heart, muscle, and kidney. Auto-enhancing processes such as these are possible causes of degenerative diseases including Parkinson's , Alzheimer's , and coronary artery disease .
The human brain has many properties that are common to all vertebrate brains. [256] Many of its features are common to all mammalian brains, [257] most notably a six-layered cerebral cortex and a set of associated structures, [258] including the hippocampus and amygdala. [259] The cortex is proportionally larger in humans than in many other ...
The rest of the brain tissue is the structural stroma that includes connective tissue such as the meninges, blood vessels, and ducts. The two main types of cells in the brain are neurons, also known as nerve cells, and glial cells, also known as neuroglia. [1] There are many types of neuron, and several types of glial cell.
In 2005 the landscape of the mammalian genome was described as numerous 'foci' of transcription that are separated by long stretches of intergenic space. [9] While some long ncRNAs are located within the intergenic stretches, the majority are overlapping sense and antisense transcripts that often include protein-coding genes, [23] giving rise to a complex hierarchy of overlapping isoforms. [24]
There are many different ways to classify neurotransmitters and are commonly classified into amino acids, monoamines and peptides. [35] Some of the major neurotransmitters are: Amino acids: glutamate, [36] aspartate, D-serine, gamma-Aminobutyric acid (GABA), [nb 1] glycine; Gasotransmitters: nitric oxide (NO), carbon monoxide (CO), hydrogen ...