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A putative biomarker for CTE is the presence in serum of autoantibodies against the brain. The autoantibodies were detected in football players who experienced a large number of head hits but no concussions, suggesting that even sub-concussive episodes may be damaging to the brain.
In the future, Stein said, researchers hope to pinpoint biomarkers that can help guide CTE diagnosis in living patients. He added, however, that the new study has gaps, since it relied on self ...
Chronic traumatic encephalopathy (CTE) is a type of brain damage that has been found in 345 of 376 deceased former National Football League (NFL) players, according to a 2023 report by the Boston University CTE Center, which has led the effort to diagnose CTE cases.
CTE has affected not only professional football players, but also athletes who played only in college or in high school. In 2005, Bennet Omalu, a forensic pathologist and neuropathologist in Pittsburgh, Pennsylvania, found CTE in the brains of Mike Webster, Terry Long, Andre Waters, Justin Strzelczyk, and Tom McHale. [3]
Koerte is well known for her research in the areas of traumatic brain injury, repetitive head impacts, neurodevelopment and cutting-edge neuroradiology. [6] [7] She was the first to show alterations in the brain's microstructure following repetitive subconcussive head impacts in young athletes without a history of concussion, as well as structural changes in ice hockey players over the course ...
CTE and other issues have been a very serious issue being caused by severe brain damage in football. ESPN states that "The brain of former Kansas City Chiefs linebacker Jovan Belcher -- the 25-year-old player who shot and killed his girlfriend in 2012 before committing suicide -- showed signs of pervasive brain damage like that found in other ...
A variety of concurrently researched biomarkers have been associated with concussions, including S100B, Tau protein and glial fibrillary acid protein (GFAP). [85] In 2018, the FDA approved Banyan Biomarkers Inc. to market devices involving the use of blood samples to evaluate concussions in adults. [ 86 ]
It's also a biomarker for CTE or punch-drunk syndrome. [14] During periods of bone inflammation, CCL11 and CCR3 are upregulated. This is associated with an increase in osteoclast activity. [15] In 2022, Monje et al demonstrated that elevated levels of CCL11 may contribute to the brain fog associated with both chemotherapy and so-called long ...