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  2. Gynecomastia - Wikipedia

    en.wikipedia.org/wiki/Gynecomastia

    Definition. Gynecomastia is the abnormal non-cancerous enlargement of one or both breasts in men due to the growth of breast tissue as a result of a hormone imbalance between estrogen and androgen. [4][5] Gynecomastia is different from "pseudogynecomastia", [5][6] which is defined as an excess of skin and/or adipose tissue in the male breasts ...

  3. Aromatase excess syndrome - Wikipedia

    en.wikipedia.org/wiki/Aromatase_excess_syndrome

    Aromatase excess syndrome (AES or AEXS) is a rarely diagnosed genetic and endocrine syndrome which is characterized by an overexpression of aromatase, the enzyme responsible for the biosynthesis of the estrogen sex hormones from the androgens, in turn resulting in excessive levels of circulating estrogens and, accordingly, symptoms of hyperestrogenism. It affects both sexes, manifesting itself ...

  4. Aromatase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Aromatase_inhibitor

    Aromatase inhibitors (AIs) are a class of drugs used in the treatment of breast cancer in postmenopausal women and in men, [1][2] and gynecomastia in men. They may also be used off-label to reduce estrogen conversion when supplementing testosterone exogenously. They may also be used for chemoprevention in women at high risk for breast cancer. Aromatase is the enzyme that catalyzes a key ...

  5. America’s Most Admired Lawbreaker - The Huffington Post

    highline.huffingtonpost.com/miracleindustry/...

    If Risperdal really caused Mr. Pledger’s gynecomastia, why is the first [person] to tell them that a lawyer, not a doctor? And if Risperdal really caused plaintiff’s gynecomastia, why do they get www-dot-whatever as their only expert?

  6. US FDA approves IntraBio's drug for rare genetic disease - AOL

    www.aol.com/news/us-fda-approves-intrabios-drug...

    The company estimates that NPC affects one in 100,000 live births. On Sept. 20, the FDA approved Zevra's drug, Miplyffa, for the treatment of NPC - the first treatment to get a nod for the condition.

  7. Hypergonadotropic hypogonadism - Wikipedia

    en.wikipedia.org/wiki/Hypergonadotropic_hypogonadism

    Hypergonadotropic hypogonadism (HH), also known as primary or peripheral / gonadal hypogonadism or primary gonadal failure, is a condition which is characterized by hypogonadism which is due to an impaired response of the gonads to the gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH), and in turn a lack of sex ...