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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Schematic structure of an antibody–drug conjugate (ADC) Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. [1] Unlike chemotherapy, ADCs are intended to target and kill tumor cells while sparing healthy cells. As of 2019, some 56 pharmaceutical companies were ...
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Print/export Download as PDF ... Antibody-drug conjugates (57 P) E. ... Pages in category "Monoclonal antibodies" The following 200 pages are in this category, out of ...
Immunoconjugates are antibodies conjugated (joined) to a second molecule, usually a toxin, radioisotope or label. [ 1 ] These conjugates are used in immunotherapy [ citation needed ] and to develop monoclonal antibody therapy as a targeted form of chemotherapy [ 2 ] when they are often known as antibody-drug conjugates .
Antibody-directed enzyme prodrug therapy (ADEPT) involves the application of cancer-associated monoclonal antibodies that are linked to a drug-activating enzyme. Systemic administration of a non-toxic agent results in the antibody's conversion to a toxic drug, resulting in a cytotoxic effect that can be targeted at malignant cells.