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Placental villous immaturity is chorionic villous development that is inappropriate for the gestational age. It is associated with diabetes mellitus [1] and fetal death near term, i.e. intrauterine demise close to the normal gestational period. [2]
The chorionic villi are at first small and non-vascular. 13–15 days: trophoblast only [1] Secondary: The villi increase in size and ramify, while the mesoderm grows into them. 16–21 days: trophoblast and mesoderm [1] Tertiary: Branches of the umbilical artery and umbilical vein grow into the mesoderm, and in this way the chorionic villi are ...
In developmental biology, choriogenesis is the formation of the chorion, an outer membrane of the placenta that eventually forms chorionic villi that allow the transfer of blood and nutrients from mother to fetus. [1]
Chorionic villi (right of image) and cartilage, i.e. fetal parts (left of image). H&E stain. Products of conception, abbreviated POC, is a medical term used for the tissue derived from the union of an egg and a sperm. It encompasses anembryonic gestation (blighted ovum) which does not have a viable embryo.
Histopathology of acute subchorionic intervillositis, with neutrophils in Langhan’s layer of fibrinoid (by the fetal surface, at the base of a chorionic villus, seen at top right). Placentitis is an inflammation of the placenta. The main forms of placentitis are: Villitis, inflammation of chorionic villi.
Image showing trophoblast differentiated into the two layers of cytotrophoblast and syncytiotrophoblast during implantation. It is the outer layer of the trophoblasts and actively invades the uterine wall, during implantation, rupturing maternal capillaries and thus establishing an interface between maternal blood and embryonic extracellular fluid, facilitating passive exchange of material ...
Histopathology of a chorionic villus, in a tubal pregnancy. The invasive lineage creates cytotrophoblasts that are essential in the process of implantation and forming a fully functional placenta. An undifferentiated cytotrophoblastic stem cell will differentiate into an extravillous cytotrophoblast intermediate and then into an interstitial ...
Commonly used criteria from Altshuler [2] [3] are: "a minimum of 10 villi, each with 10 or more vascular channels, in 10 or more areas of 3 or more random, non-infarcted placental areas when using a ×10 ocular." The Altshuler criteria are not theoretically rigorous, as they do not define the area. Normal villi have up to five vascular channels ...