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The primary function of most neurotransmitter transporters is to facilitate neurotransmitter reuptake (i.e., the reabsorption of neurotransmitters by the cell which released them). [ 1 ] [ 2 ] [ 6 ] During neurotransmitter reuptake, neurotransmitter transporters will move specific types of neurotransmitters from the extracellular space into the ...
The cells of the brain include neurons and supportive glial cells. There are more than 86 billion neurons in the brain, and a more or less equal number of other cells. Brain activity is made possible by the interconnections of neurons and their release of neurotransmitters in response to nerve impulses.
HD cells are found in many brain areas, including the cortical regions of postsubiculum (also known as the dorsal presubiculum), retrosplenial cortex, [10] and entorhinal cortex, [11] and subcortical regions including the thalamus (the anterior dorsal [12] and the lateral dorsal [13] thalamic nuclei), lateral mammillary nucleus, [14] dorsal ...
Micrograph showing a von Economo neuron of the cingulate. HE-LFB stain.. Von Economo neurons, also called spindle neurons, are a specific class of mammalian cortical neurons characterized by a large spindle-shaped soma (or body) gradually tapering into a single apical axon (the ramification that transmits signals) in one direction, with only a single dendrite (the ramification that receives ...
Brain cells make up the functional tissue of the brain. The rest of the brain tissue is the structural stroma that includes connective tissue such as the meninges, blood vessels, and ducts. The two main types of cells in the brain are neurons, also known as nerve cells, and glial cells, also known as neuroglia. [1]
EPSPs in living cells are caused chemically. When an active presynaptic cell releases neurotransmitters into the synapse, some of them bind to receptors on the postsynaptic cell. Many of these receptors contain an ion channel capable of passing positively charged ions either into or out of the cell (such receptors are called ionotropic receptors).
The size of the neuron can also affect the inhibitory postsynaptic potential. Simple temporal summation of postsynaptic potentials occurs in smaller neurons, whereas in larger neurons larger numbers of synapses and ionotropic receptors as well as a longer distance from the synapse to the soma enables the prolongation of interactions between neurons.
Endogenous regeneration in the brain is the ability of cells to engage in the repair and regeneration process. While the brain has a limited capacity for regeneration, endogenous neural stem cells, as well as numerous pro-regenerative molecules, can participate in replacing and repairing damaged or diseased neurons and glial cells.