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However, these cells did not self-renew and were subsequently depleted as they generated new neurons, thus failing to satisfy the requirement for stem cells. [6] [7] One study observed that ependymal cells from the lining of the lateral ventricle might be a source for cells which can be transplanted into the cochlea to reverse hearing loss. [8]
This schematic illustrates the four different types of glial cells, all of which possess cytoplasmic processes: ependymal cells (light pink), astrocytes (green), microglia (red), and oligodendrocytes (light blue). Cell bodies of neurons are in yellow (Their axons are surrounded by myelin, produced by oligodendrocytes).
Tanycytes are highly specialized ependymal cells found in the third ventricle of the brain, and on the floor of the fourth ventricle. Each tanycyte has a long basal process that extends deep into the hypothalamus. It is possible that their function is to transfer chemical signals from the cerebrospinal fluid to the central nervous system.
Oligodendrocytes are a type of glial cell, non-neuronal cells in the central nervous system.They arise during development from oligodendrocyte precursor cells (OPCs), [8] which can be identified by their expression of a number of antigens, including the ganglioside GD3, [9] [10] [11] the NG2 chondroitin sulfate proteoglycan, and the platelet-derived growth factor-alpha receptor subunit (PDGF ...
When scientists use a traditional microscope to observe a cell, they use stains -- chemicals that color parts of the cell to make them visible. However, these stains cause damage and kill the cell ...
Progenitor ependymal cells are monociliated but they differentiate into multiciliated ependymal cells. [6] [7] Unlike the ependyma, the choroid plexus epithelial layer has tight junctions [8] between the cells on the side facing the ventricle (apical surface). These tight junctions prevent the majority of substances from crossing the cell layer ...
As the cells grow, the neurite tangle remains centrally located and the cell bodies are squeezed to the periphery, thus explaining the rosette pattern. Depending upon their location, ependymal cells may display 2 cell poles. A luminal pole projects to the ependymal lining of a ventricle and a "submesenchymal pole" projects toward the surface of ...
The tela choroidea is a very thin part of the loose connective tissue of pia mater overlying and closely adhering to the ependyma. [ 2 ] [ 1 ] It has a rich blood supply. The ependyma and vascular pia mater – the tela choroidea, form regions of minute projections known as a choroid plexus that projects into each ventricle.