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Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
Dronabinol is the INN for delta-9-THC [157] [158] (there is a common confusion according to which the word "dronabinol" would only refer to synthetic delta-9-THC, which is incorrect [159]). Cannabidiol is also the official INN for the molecule, granted in 2017. [160] Nabilone is the INN for a synthetic cannabinoid analog (not present in ...
It may also be useful in the treatment of severe mania that is non-responsive to medications. [81] [82] The most frequent side effects of ECT include memory impairment, headaches, and muscle aches. [14] In some instances, ECT can produce significant and long-lasting cognitive impairment, including anterograde amnesia, and retrograde amnesia. [83]
In Phase III trials, the most common adverse effects were dizziness, drowsiness and disorientation; 12% of subjects stopped taking the drug because of the side effects. [57] Dronabinol (brand names Marinol and Syndros) is a delta-9-THC containing drug for treating HIV/AIDS-induced anorexia and chemotherapy-induced nausea and vomiting. [58]
The short-term effects of cannabis are caused by many chemical compounds in the cannabis plant, including 113 [clarification needed] different cannabinoids, such as tetrahydrocannabinol, and 120 terpenes, [1] which allow its drug to have various psychological and physiological effects on the human body.
Tetrahydrocannabinol (THC) is a cannabinoid found in cannabis. [9] It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant.
The Δ 9 isomer of THCP occurs naturally in cannabis, but in small amounts. A 2021 study reported the content of Δ 9 -THCP ranging from 0.0023% to 0.0136% (w/w) (approximately 0.02–0.13 mg/g) without correlation to THC percentage in Δ 9 -THC -dominant strains of cannabis; that study failed to detect THCP in CBD -dominant strains.
Δ 9-Tetrahydrocannabiorcol (Δ 9-THCC, (C1)-Δ 9-THC) is a phytocannabinoid found in Cannabis pollen. [1] It is a homologue of THC and THCV with the alkyl side chain replaced by a smaller methyl group.