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The National Institutes of Health (NIH) maintains a database, which contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant. Suggested therapeutic alternatives ...
There are multiple routes that a treatment can enter into the breast milk. One route is through a breastfeeding mother. When a mother that is lactating receives a treatment including but not limited to prescription medication, over-the-counter medications, or herbal remedies, these compounds can make their way into the mother’s milk and are subsequently delivered to an infant via ...
Contraindications to breastfeeding are those conditions that could compromise the health of the infant if breast milk from their mother is consumed. Examples include galactosemia , untreated HIV , untreated active tuberculosis , Human T-lymphotropic virus 1 or II , uses illicit drugs , or mothers undergoing chemotherapy or radiation treatment .
Side effects may include bleeding, most commonly from the nose, gastrointestinal tract (GI) or genitourinary system. [2] Compared to the risk of bleeding with warfarin use, direct factor Xa inhibitors have a higher risk of GI bleeding, but lower risk of bleeding in the brain. [2]
Warfarin interacts with many commonly used drugs, and the metabolism of warfarin varies greatly between patients. [27] Some foods have also been reported to interact with warfarin. [27] Apart from the metabolic interactions, highly protein bound drugs can displace warfarin from serum albumin and cause an increase in the INR. [63]
The prophylactic antibiotic use of human milk may be important in areas where mothers and infants do not have easy access to medicine, such as people living in developing countries. [24] Under these circumstances, practice of HBM therapy as medicine will be a determining factor in infant recovery and survival.
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Thin-film drug delivery uses a dissolving film or oral drug strip to administer drugs via absorption in the mouth (buccally or sublingually) and/or via the small intestines (enterically). A film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering the drug to the systemic circulation via ...