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Images of CAA collected at 1.5 T. Left, conventional T2* (TE=20 ms), center, SWI processed magnitude image (TE=40 ms) and right, SWI phase image (TE=40 ms) Gradient recalled echo (GRE) imaging is the conventional way to detect hemorrhage in CAA , however SWI is a much more sensitive technique that can reveal many micro-hemorrhages that are ...
Intracranial hemorrhage (ICH), also known as intracranial bleed, is bleeding within the skull. [1] Subtypes are intracerebral bleeds (intraventricular bleeds and intraparenchymal bleeds), subarachnoid bleeds, epidural bleeds, and subdural bleeds. [2] Intracerebral bleeding affects 2.5 per 10,000 people each year. [1]
SOD1 binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide.
A procedure to place an external ventricular drain may be used to treat hydrocephalus or increased intracranial pressure, however, the use of corticosteroids is frequently avoided. [1] Sometimes surgery to directly remove the blood can be therapeutic. [1] Cerebral bleeding affects about 2.5 per 10,000 people each year. [2]
The Corrupted Blood debuff being spread among characters in Ironforge, one of World of Warcraft's in-game cities. The Corrupted Blood incident (also known as the World of Warcraft pandemic) [1] [2] took place between September 13 and October 8, 2005, in World of Warcraft, a massively multiplayer online role-playing game (MMORPG) developed by Blizzard Entertainment.
The original Thottbot was a news aggregator created by Bill "Aftathott" Dyess, founder of the EverQuest guild "Afterlife", in March 2001. Its purpose was to comb various video game websites for news and information on a number of MMORPGs with a focus on EverQuest, and later grew to include other games such as PlanetSide, Meridian 59, Dark Age of Camelot, and World of Warcraft. [4]
ARIA-E refers to cerebral edema, involving the breakdown of the tight endothelial junctions of the blood-brain barrier and subsequent accumulation of fluid. [3] In a double-blind trial of the humanised monoclonal antibody solanezumab (n = 2042), sixteen patients (11 taking the drug, 5 taking a placebo), or 0.78% developed ARIA-E.
The underlying pathology of CADASIL is progressive hypertrophy of the smooth muscle cells in blood vessels. Autosomal dominant mutations in the NOTCH3 gene (on the long arm of chromosome 19) cause an abnormal accumulation of Notch 3 protein at the cytoplasmic membrane of vascular smooth muscle cells both in cerebral and extracerebral vessels, [8] seen as granular osmiophilic deposits on ...