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Serum vitamin B 12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin , while only 6–20% is binds to transcobalamin ll. [ 2 ] Only transcobalamin ll is "active" and can be used by the body. [ 1 ]
Diagnosing Vitamin B12 Deficiency and Cancer [38] If cancer is suspected as the cause of vitamin B12 deficiency, several diagnostic steps are necessary: Blood Tests: A simple blood test can measure vitamin B12 levels, along with other markers such as homocysteine and methylmalonic acid, which may also indicate a deficiency.
[6] [15] [26] Vitamin B 12 deficiency can also cause symptoms of mania and psychosis. [27] [28] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur. [29] The main type of vitamin B12 deficiency anemia is pernicious anemia, [30] characterized by a triad of symptoms:
Lack of vitamin B12 can cause megaloblastic anemia—a condition characterized by larger than normal red blood cells in a smaller than normal amount. This causes fatigue, paleness in the skin ...
Vitamin B12 is needed to create healthy red blood cells. Your body can end up making fewer red blood cells if you have a vitamin B12 deficiency, leading to a specific type of anemia, according to ...
Acid–base and blood gases are among the few blood constituents that exhibit substantial difference between arterial and venous values. [6] Still, pH, bicarbonate and base excess show a high level of inter-method reliability between arterial and venous tests, so arterial and venous values are roughly equivalent for these. [44]
If there are other, reversible causes of low vitamin B 12 levels, the cause must be treated. [106] Vitamin B 12 deficiency anemia is usually easily treated by providing the necessary level of vitamin B 12 supplementation. [107] The injections are quick-acting, and symptoms usually go away within one to two weeks. [107]
Anemia is a deficiency in the size or number of red blood cells or in the amount of hemoglobin they contain. [1] This deficiency limits the exchange of O 2 and CO 2 between the blood and the tissue cells. [1] Globally, young children, women, and older adults are at the highest risk of developing anemia. [1]