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After diagnosis of MS, characteristics that predict a worse course are male sex, older age, and greater disability at the time of diagnosis; female sex is associated with a higher relapse rate. [209] Currently, no biomarker can accurately predict disease progression in every patient. [ 205 ]
Nearly 2.8 million people live with multiple sclerosis—here’s what you need to know about it, including symptoms, genetic or other risk factors, and when to see a doctor.
Currently it is unknown what the primary cause of MS is; if MS is a heterogeneous disease, the lesion development process would not be unique. In particular, some PPMS patients having a special clinical course named rapidly progressive multiple sclerosis could have a special genetic cause [47] and a different development process.
Unusual types of MS have been described; these include Devic's disease, Balo concentric sclerosis, Schilder's diffuse sclerosis, and Marburg multiple sclerosis. There is debate on whether they are MS variants or different diseases. [31] Multiple sclerosis behaves differently in children, taking more time to reach the progressive stage. [5]
A new study found that in about 10% cases of multiple sclerosis, the body begins producing a distinctive set of antibodies against its own proteins years before symptoms emerge. “Multiple ...
Multiple Sclerosis diagnoses have been rising globally since 2013, and in 2019, ... and in 2019, an estimated 1 million people had MS. Doctors are trying to figure out why.
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