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Similar to other rodenticides, the preparation requires 3–7 days to be effective. Rather than killing rodents through internal haemorrhaging as anticoagulants do, [9] PCC affects a rodent’s digestive system, causing acute dehydration due to its extremely absorptive nature (corn cob has been used in applications such as oil spills in water bodies, seed drying and de-icing). [10]
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Chlorophacinone is a first-generation anticoagulant rodenticide.The mechanism of action results in internal bleeding due to non-functional clotting factors. It was used as a toxin to control rodent populations.
Insecticides, larvicides, rodenticides, Lethal ovitraps and repellents can be used to control vectors. For example, larvicides can be used in mosquito breeding zones; insecticides can be applied to house walls or bed nets, and use of personal repellents can reduce incidence of insect bites and thus infection.
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Norbormide (Raticate, Shoxin) is a toxic compound used as a rodenticide.It has several mechanisms of action, acting as a vasoconstrictor and calcium channel blocker, [1] but is selectively toxic to rats and has relatively low toxicity to other species, due to a species specific action of opening the permeability transition pores in rat mitochondria.
Warning label on a tube of rat poison containing bromadiolone on a dike of the Scheldt river in Steendorp, Belgium. Bromadiolone is a potent anticoagulant rodenticide.It is a second-generation 4-hydroxycoumarin derivative and vitamin K antagonist, often called a "super-warfarin" for its added potency and tendency to accumulate in the liver of the poisoned organism.
Flocoumafen is a fluorinated, second-generation anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. [1] It is a second generation (i.e., high potency) chemical in this class, used commercially as a rodenticide.