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Plasmodium falciparum is a unicellular protozoan parasite of humans, and the deadliest species of Plasmodium that causes malaria in humans. [2] The parasite is transmitted through the bite of a female Anopheles mosquito and causes the disease's most dangerous form, falciparum malaria.
Chloroquine is only recommended as a prophylactic drug in regions only affected by P. vivax and sensitive P. falciparum strains. Chloroquine has been used in the treatment of malaria for many years and no abortifacient or teratogenic effects have been reported during this time; therefore, it is considered very safe to use during pregnancy.
Artemether is an antimalarial drug for uncomplicated malaria caused by P. falciparum (and chloroquine-resistant P. falciparum) or chloroquine-resistant P. vivax parasites. [1] [7] Artemether can also be used to treat severe malaria. [2]
Plasmodium malariae is a parasitic protozoan that causes malaria in humans. It is one of several species of Plasmodium parasites that infect other organisms as pathogens, also including Plasmodium falciparum and Plasmodium vivax, responsible for most malarial infection.
Artemisinin (/ ˌ ɑːr t ɪ ˈ m iː s ɪ n ɪ n /) and its semisynthetic derivatives are a group of drugs used in the treatment of malaria due to Plasmodium falciparum. [1] It was discovered in 1972 by Tu Youyou, who shared the 2015 Nobel Prize in Physiology or Medicine for her discovery. [2]
Ganaplacide (development codename KAF156) is a drug in development by Novartis for the purpose of treating malaria. It is a imidazolopiperazine derivative. [1] [2] It has shown activity against the Plasmodium falciparum and Plasmodium vivax forms of the malaria parasite. [3]
Hence, its geographical distribution is overlapping with areas of high malaria prevalence rates and the occurrence of drug resistant Plasmodium falciparum. [5] P. falciparum is one of the four main protozoan parasites that cause malaria and is one of the leading causes of malaria deaths. This species complex is of high medical importance for ...
Amodiaquine (ADQ) is a medication used to treat malaria, including Plasmodium falciparum malaria when uncomplicated. [2] [3] It is recommended to be given with artesunate to reduce the risk of resistance. [2] Due to the risk of rare but serious side effects, it is not generally recommended to prevent malaria. [2]