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Azadirachta indica, commonly known as neem, margosa, nimtree or Indian lilac, [3] is a tree in the mahogany family Meliaceae. It is one of the two species in the genus Azadirachta . It is native to the Indian subcontinent and to parts of Southeast Asia , but is naturalized and grown around the world in tropical and subtropical areas.
Treatment “Mild cases may be managed with frequent thick moisturizing and use of topical medications, while more severe cases can require the same in addition to phototherapy or systemic ...
Beyond adverse effects from the herb itself, "adulteration, inappropriate formulation, or lack of understanding of plant and drug interactions have led to adverse reactions that are sometimes life threatening or lethal." [3]
Representation of nimbin analog N2. Nimbin is a triterpenoid isolated from the neem tree (Azadirachta indica).Nimbin is thought to be responsible for much of the biological activities of neem oil, and is reported to have anti-inflammatory, antipyretic, fungicidal, antihistamine and antiseptic properties. [2]
When eczema is severe and does not respond to other forms of treatment, systemic immunosuppressants are sometimes used. Immunosuppressants can cause significant side effects and some require regular blood tests. The most commonly used are ciclosporin, azathioprine, and methotrexate.
The ingestion of neem oil is potentially toxic and can cause metabolic acidosis, seizures, kidney failure, encephalopathy and severe brain ischemia in infants and young children. [ 2 ] [ 8 ] [ 9 ] Neem oil should not be consumed alone without any other solutions, particularly by pregnant women, women trying to conceive or children. [ 2 ]
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