Search results
Results From The WOW.Com Content Network
The late onset of Huntington's disease means it does not usually affect reproduction. [26] The worldwide prevalence of HD is 5–10 cases per 100,000 persons, [100] [101] but varies greatly geographically as a result of ethnicity, local migration and past immigration patterns. [26] Prevalence is similar for men and women.
Thirteen has a 50/50 chance of having inherited Huntington's disease from her mother, but she initially refuses to be tested for it as not knowing allows her to live with hope. In the fourth-season finale, Thirteen takes the test and is diagnosed as having the mutated Huntington gene. [4]
Huntingtin. Huntingtin (Htt) is the protein coded for in humans by the HTT gene, also known as the IT15 ("interesting transcript 15") gene. [5] Mutated HTT is the cause of Huntington's disease (HD), and has been investigated for this role and also for its involvement in long-term memory storage. [6]
George Huntington (April 9, 1850 – March 3, 1916) was an American physician who contributed a classic clinical description of the disease that bears his name— Huntington's disease. [1] Huntington described this condition in the first of only two scientific papers he ever wrote. He wrote this paper when he was 22, a year after receiving his ...
Huntington built its first five-story building in 1878, on the intersection's southwest corner. Four of P. W.'s five sons became partners during the 1890s and early 1900s. The bank was incorporated in 1905 as The Huntington National Bank of Columbus. [12] Huntington died in 1918 shortly after turning the bank over to his sons. [13]
A trinucleotide repeat expansion, also known as a triplet repeat expansion, is the DNA mutation responsible for causing any type of disorder categorized as a trinucleotide repeat disorder. These are labelled in dynamical genetics as dynamic mutations. [1] Triplet expansion is caused by slippage during DNA replication, also known as "copy choice ...
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease of mainly the central nervous system that affects both the motor and non-motor systems of the body. The symptoms usually emerge slowly, and, as the disease progresses, non-motor symptoms become more common. Usual symptoms include tremors, slowness of movement ...
None of Guthrie's three surviving children with Marjorie have developed symptoms of Huntington's. His son Bill with his first wife Mary Guthrie died in an auto-train accident in Pomona, California, at the age of 23. [108] His and Mary's two daughters, Gwendolyn and Sue, both suffered from Huntington's disease. They each died at age 41. [109]