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Interleukin 21. Interleukin 21 (IL-21) is a protein that in humans is encoded by the IL21 gene. [5][6][7] Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. [5][8] This cytokine induces cell ...
Interleukin 21 receptor is a type I cytokine receptor. IL21R is its human gene.. The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma chain (γc), a receptor subunit also shared by the receptors for interleukin 2 (IL2), interleukin 7 (IL7 ...
Illinois Route 21 (IL 21) is an arterial north–south state highway in northeastern Illinois. It runs from Illinois Route 43 (Harlem Avenue) in Niles to U.S. Route 41 (Skokie Highway) north of Gurnee. Illinois 21 is 28.13 miles (45.27 km) long. [1] Along most of its length, Illinois 21 is called Milwaukee Avenue.
In structure, IL-10 is a protein of about 160 amino acids that contains four conserved cysteines involved in disulphide bonds. [33] IL-10 is highly similar to the Human herpesvirus 4 (Epstein-Barr virus) BCRF1 protein, which inhibits the synthesis of gamma-interferon and to Equid herpesvirus 2 (Equine herpesvirus 2) protein E7. It is also ...
In this way, IL-1β, IL-1α, IL-36α, IL-36β, IL-36γ, IL-36RA, IL-37, IL-38, and IL-1RA are very likely ancestral family members sharing a common lineage. [9] However, IL-18 and IL-33 are on different chromosomes and there is insufficient sequence or chromosomal anatomy evidence to suggest they share common ancestry with the other IL-1 ...
The common gamma chain (γ c) (or CD132), also known as interleukin-2 receptor subunit gamma or IL-2RG, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, [5] IL-7, [6] IL-9, IL-15 [7] and interleukin-21 receptor. The γ c glycoprotein is a member of the type I ...
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein [5] that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating ...
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