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The history of coronaviruses is an account of the discovery of the diseases caused by coronaviruses and the diseases they cause. It starts with the first report of a new type of upper-respiratory tract disease among chickens in the U.S. state of North Dakota, in 1931. The causative agent was identified as a virus in 1933.
Please help update this template to reflect recent events or newly available information. Relevant discussion may be found on the talk page . Main article: Statistics of the COVID-19 pandemic in the United States
The timeline of the COVID-19 pandemic lists the articles containing the chronology and epidemiology of SARS-CoV-2, [1] the virus that causes the coronavirus disease 2019 and is responsible for the COVID-19 pandemic. The first human cases of COVID-19 occurred in Wuhan, People's Republic of China, on or about 17 November 2019. [2]
The first demonstration of phagocytosis as a property of leukocytes, the immune cells, was from the German zoologist Ernst Haeckel. [14] [15] In 1846, English physician Thomas Wharton Jones had discovered that a group of leucocytes, which he called "granule-cell" (later renamed and identified as eosinophil [16]), could change shape, the phenomenon later called amoeboid movement.
Cell-mediated immunity is directed primarily at microbes that survive in phagocytes and microbes that infect non-phagocytic cells. It is most effective in removing virus-infected cells, but also participates in defending against fungi, protozoans, cancers, and intracellular bacteria.
GX_P2V is a COVID-19 mutant strain that is fatal to humanized mice with the hACE2 gene. [ 1 ] The Chinese government has been performing tests on GX_P2V and has published a new study. [ 2 ] “ This underscores a spillover risk of GX_P2V into humans and provides a unique model for understanding the pathogenic mechanisms of SARS-CoV-2 related ...
Johns Hopkins Coronavirus Resource Center: Global aggregated data including cases, testing, contact tracing, and vaccine development [12]; World Health Organization (WHO) Coronavirus Disease Dashboard: a database of confirmed cases and deaths reported globally and broken down by region. [13]
Subsequently, the virus in this clade of coronaviruses acquires HE to help the virus get rid of infected cells, but later the NTD of the mouse coronavirus evolved into a new structure that can be associated with the protein receptor mCEACAM1. Combination greatly increases the binding ability of viruses and murine cells.