Search results
Results From The WOW.Com Content Network
The fluorescent treponemal antibody absorption (FTA-ABS) test is a diagnostic test for syphilis.Using antibodies specific for the Treponema pallidum species, such tests would be assumed to be more specific than non-treponemal testing such as VDRL but have been shown repeatedly to be sensitive but not specific for the diagnosis of neurosyphilis in cerebrospinal fluid (CSF).
There are a number of treponemal-specific tests such as the fluorescent treponemal antibody-absorption test, T. pallidum hemagglutination assays , and the microhemagglutination assay . [citation needed] The MHA-TP is used to confirm a syphilis infection after another method tests positive for the syphilis bacteria.
Fig. 1: Microwells showing positive and negative TPHA test. The Treponema pallidum particle agglutination assay (also called TPPA test) is an indirect agglutination assay used for detection and titration of antibodies against the causative agent of syphilis, Treponema pallidum subspecies pallidum. It also detects other treponematoses. [citation ...
The rapid plasma reagin test (RPR test or RPR titer) is a type of rapid diagnostic test that looks for non-specific antibodies in the blood of the patient that may indicate an infection by syphilis or related non-venereal treponematoses. It is one of several nontreponemal tests for syphilis (along with the Wassermann test and the VDRL test).
Treponemal antibody tests usually become positive two to five weeks after the initial infection [22] and remain positive for many years. [43] Neurosyphilis is diagnosed by finding high numbers of leukocytes (predominately lymphocytes ) and high protein levels in the cerebrospinal fluid in the setting of a known syphilis infection.
Pleocytosis, raised CSF protein level and positive CSF serology suggest neurosyphilis. [31] CSF VDRL is 50-90% specific for neurosyphilis. [18] 60% of newborns with congenital syphilis also have neurosyphilis. [18] Non-treponemal titers should be monitored in the newborns every 2-3 months to ensure an adequate response to treatment. [18]
ICD-10 is the 10th revision of the International Classification of Diseases (ICD), a medical classification list by the World Health Organization (WHO). It contains codes for diseases, signs and symptoms, abnormal findings, complaints, social circumstances, and external causes of injury or diseases. [1]
The Wassermann test or Wassermann reaction (WR) [1] is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly