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Norepinephrine, also known as noradrenaline and sold under the brand name Levophed among others, is a medication used to treat people with very low blood pressure. [2] It is the typical medication used in sepsis if low blood pressure does not improve following intravenous fluids. [3]
Their uses include treatment of cardiovascular problems, shock, and a variety of psychiatric conditions. These drugs are divided into: sympathomimetic drugs which mimic or enhance at least some of the effects of norepinephrine released by the sympathetic nervous system; sympatholytic drugs, in contrast, block at least some of the effects. [ 36 ]
Vasodilatory shock, vasogenic shock, or vasoplegic shock is a medical emergency belonging to shock along with cardiogenic shock, septic shock, allergen-induced shock and hypovolemic shock. When the blood vessels suddenly relax, it results in vasodilation .
Shock from blood loss occurs in about 1–2% of trauma cases. [34] Overall, up to one-third of people admitted to the intensive care unit (ICU) are in circulatory shock. [42] Of these, cardiogenic shock accounts for approximately 20%, hypovolemic about 20%, and septic shock about 60% of cases. [43]
Cardiogenic shock is a medical emergency resulting from inadequate blood flow to the body's organs due to the dysfunction of the heart. Signs of inadequate blood flow include low urine production (<30 mL/hour), cool arms and legs, and decreased level of consciousness.
The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β 2) antagonists and alpha-2 (α 2) agonists, which are used to treat high ...
Cardiogenic Shock: Resulting from heart dysfunction, such as myocardial infarction or heart failure, cardiogenic shock shows a decreased CI and increased systemic vascular resistance (SVR). Obstructive Shock : Caused by obstructions like cardiac tamponade or massive pulmonary embolism , this type of shock also presents with a decreased CI, but ...
Onset may be rapid (acute) or more gradual (subacute). [10] [2] Signs of cardiac tamponade typically include those of cardiogenic shock including shortness of breath, weakness, lightheadedness, cough [1] and those of Beck's triad e.g. jugular vein distention, quiet heart sounds and hypotension.