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Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]
Sildenafil can still be used to treat hypertension, but today, the primary use of this PDE5 inhibitor is to remedy ED. Other first-line treatment options for blood pressure and heart disease are ...
Viagra (or sildenafil) lasts three to five hours after it’s consumed. Cialis (tadalafil) has a half-life of 17.5 hours, meaning this drug lasts up to 36 hours after it’s consumed.
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
In many of these studies, the researchers found more than 10 percent of men having intimacy with men used sildenafil citrate — and that its use is associated with higher risks of unprotected ...
The PDE5 inhibitors sildenafil (Viagra), vardenafil (Levitra) and tadalafil (Cialis) are prescription drugs which are taken by mouth. [10]: 20–21 As of 2018, sildenafil is available in the UK without a prescription. [54]
How to Use Viagra for Best Results. Viagra is great as an ED treatment, but taking it in particular conditions can make it even more effective. To get the best results from Viagra when treating ...
The UK online pharmacy market has been subject to official regulation since the first legal online pharmacy was set up in 2002. In 2005 changes to the National Health Service regulation made it legal for online pharmacies to fill out NHS prescriptions over the internet. In general, online pharmacies in the UK are subject to the same statutory ...