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  2. Lower motor neuron lesion - Wikipedia

    en.wikipedia.org/wiki/Lower_motor_neuron_lesion

    A lower motor neuron lesion is a lesion which affects nerve fibers traveling from the lower motor neuron(s) in the anterior horn/anterior grey column of the spinal cord, or in the motor nuclei of the cranial nerves, to the relevant muscle(s). [1]

  3. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Motor neuron disease can affect either upper motor neurons (UMNs) or lower motor neurons (LMNs). Motor neuron disease describes a collection of clinical disorders, characterized by progressive muscle weakness and the degeneration of the motor neuron on electrophysiological testing. The term "motor neuron disease" has varying meanings in ...

  4. Hyporeflexia - Wikipedia

    en.wikipedia.org/wiki/Hyporeflexia

    The upper motor neurons are thought to inhibit the reflex arc, which is formed by sensory neurons from intrafusal fibers of muscles, lower motor neurons (including alpha and gamma motor fibers) and appurtenant interneurons. Therefore, damage to lower motor neurons will subsequently result in hyporeflexia and/or areflexia. [citation needed]

  5. Myelopathy - Wikipedia

    en.wikipedia.org/wiki/Myelopathy

    Upper motor neuron signs—weakness, spasticity, clumsiness, altered tonus, hyperreflexia and pathological reflexes, including Hoffmann's sign and inverted plantar reflex (positive Babinski sign) Lower motor neuron signs—weakness, clumsiness in the muscle group innervated at the level of spinal cord compromise, muscle atrophy, hyporeflexia ...

  6. Multifocal motor neuropathy - Wikipedia

    en.wikipedia.org/wiki/Multifocal_motor_neuropathy

    Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken. The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present.

  7. Lower motor neuron - Wikipedia

    en.wikipedia.org/wiki/Lower_motor_neuron

    Glutamate released from the upper motor neurons triggers depolarization in the lower motor neurons in the anterior grey column, which in turn causes an action potential to propagate the length of the axon to the neuromuscular junction where acetylcholine is released to carry the signal across the synaptic cleft to the postsynaptic receptors of the muscle cell membrane, signaling the muscle to ...

  8. Progressive muscular atrophy - Wikipedia

    en.wikipedia.org/wiki/Progressive_muscular_atrophy

    PMA is classified among motor neuron diseases (MND) where it is thought to account for around 4% of all MND cases. [ 1 ] PMA affects only the lower motor neurons , in contrast to amyotrophic lateral sclerosis (ALS), the most common MND, which affects both the upper and lower motor neurons, or primary lateral sclerosis , another MND, which ...

  9. Flaccid dysarthria - Wikipedia

    en.wikipedia.org/wiki/Flaccid_dysarthria

    Flaccid dysarthria is a motor speech disorder resulting from damage to peripheral nervous system (cranial or spinal nerves) or lower motor neuron system. Depending on which nerves are damaged, flaccid dysarthria affects respiration, phonation, resonance, and articulation.