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  2. Elevated alpha-fetoprotein - Wikipedia

    en.wikipedia.org/wiki/Elevated_alpha-fetoprotein

    Elevated alpha-fetoprotein refers to a state where alpha-fetoprotein levels are outside of the reference range. There are two categories of AFP tests: tests performed on serum (blood plasma), and tests performed on amniotic fluid. Tests performed on serum are further categorized by the reason for performing the test: maternal serum, adult tumor ...

  3. Liver tumor - Wikipedia

    en.wikipedia.org/wiki/Liver_tumor

    Currently, if the hepatic adenoma is >5 cm, increasing in size, symptomatic lesions, has molecular markers associated with HCC transformation, rising level of liver tumor markers such as alpha fetoprotein, the patient is a male, or has a glycogen storage disorder, the adenoma is recommended to be surgically removed. [7]

  4. Liver cancer - Wikipedia

    en.wikipedia.org/wiki/Liver_cancer

    High levels of alpha-fetoprotein (AFP) in the blood can be found in many cases of HCC and intrahepatic cholangiocarcinoma. [17] Of note, AFP is most useful for monitoring if liver cancers come back after treatment rather than for initial diagnosis. [17]

  5. Alpha-fetoprotein - Wikipedia

    en.wikipedia.org/wiki/Alpha-fetoprotein

    Alpha-fetoprotein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein, alpha-fetoglobulin, or alpha fetal protein) is a protein [5] [6] that in humans is encoded by the AFP gene. [ 7 ] [ 8 ] The AFP gene is located on the q arm of chromosome 4 (4q13.3). [ 9 ]

  6. Liver function tests - Wikipedia

    en.wikipedia.org/wiki/Liver_function_tests

    Alpha-fetoprotein (AFP) is significantly expressed in foetal liver. However, the mechanism that led to the suppression of AFP synthesis in adults is not fully known. Exposure of the liver to cancer-causing agents and arrest of liver maturation in childhood can lead to the rise in AFP. AFP can reach until 400–500 μg/L in hepatocellular ...

  7. Hepatoblastoma - Wikipedia

    en.wikipedia.org/wiki/Hepatoblastoma

    The most common method of testing for hepatoblastoma is a blood test checking the alpha-fetoprotein level. Alpha-fetoprotein (AFP) is used as a biomarker to help determine the presence of liver cancer in children. At birth, infants have relatively high levels of AFP, which fall to normal adult levels by the second year of life. The normal level ...

  8. Oncofetal antigen - Wikipedia

    en.wikipedia.org/wiki/Oncofetal_antigen

    These proteins are often measurable in the blood of individuals with cancer and may be used to both diagnose and follow treatment of the tumors. One example of an oncofetal antigen is alpha-fetoprotein , which is produced by hepatocellular carcinoma and some germ cell tumors .

  9. Hepatocellular carcinoma - Wikipedia

    en.wikipedia.org/wiki/Hepatocellular_carcinoma

    Hepatocellular carcinoma (HCC [1]) is the most common type of primary liver cancer in adults and is currently the most common cause of death in people with cirrhosis. [2] HCC is the third leading cause of cancer-related deaths worldwide.