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  2. Tetracycline-controlled transcriptional activation - Wikipedia

    en.wikipedia.org/wiki/Tetracycline-controlled...

    A Tet-On system works similarly, but in the opposite fashion. While in a Tet-Off system, tTA is capable of binding the operator only if not bound to tetracycline or one of its derivatives, such as doxycycline, in a Tet-On system, the rtTA protein is capable of binding the operator only if bound by a tetracycline. Thus the introduction of ...

  3. TetR - Wikipedia

    en.wikipedia.org/wiki/TetR

    Tet Repressor proteins (otherwise known as TetR) are proteins playing an important role in conferring antibiotic resistance to large categories of bacterial species. Tetracycline (Tc) is a broad family of antibiotics to which bacteria have evolved resistance. Tc normally kills bacteria by binding to the bacterial ribosome and halting protein ...

  4. Biomolecular gradient - Wikipedia

    en.wikipedia.org/wiki/Biomolecular_gradient

    A biomolecular gradient can exist intracellularly (within a cell) or extracellularly (between groups of cells). The purposes of such gradients in biological systems vary, but include chemotaxis and functions in development. These types of gradients play a role in many different types of signaling as well as recently being implicated in cancer ...

  5. Active transport - Wikipedia

    en.wikipedia.org/wiki/Active_transport

    In cellular biology, active transport is the movement of molecules or ions across a cell membrane from a region of lower concentration to a region of higher concentration—against the concentration gradient. Active transport requires cellular energy to achieve this movement.

  6. TET enzymes - Wikipedia

    en.wikipedia.org/wiki/TET_enzymes

    The TET enzymes are a family of ten-eleven translocation (TET) methylcytosine dioxygenases. They are instrumental in DNA demethylation . 5-Methylcytosine (see first Figure) is a methylated form of the DNA base cytosine (C) that often regulates gene transcription and has several other functions in the genome.

  7. French flag model - Wikipedia

    en.wikipedia.org/wiki/French_flag_model

    In the French flag model, the French flag is used to represent the effect of a morphogen on cell differentiation: a morphogen affects cell states based on concentration, these states are represented by the different colors of the French flag: high concentrations activate a "blue" gene, lower concentrations activate a "white" gene, with "red" serving as the default state in cells below the ...

  8. Transcellular transport - Wikipedia

    en.wikipedia.org/wiki/Transcellular_transport

    Facilitated diffusion is the movement of polar molecules down the concentration gradient with the assistance of membrane proteins. Since the molecules associated with facilitated diffusion are polar, they are repelled by the hydrophobic sections of permeable membrane, therefore they need to be assisted by the membrane proteins.

  9. Symporter - Wikipedia

    en.wikipedia.org/wiki/Symporter

    Typically, the ion(s) will move down the electrochemical gradient, allowing the other molecule(s) to move against the concentration gradient. The movement of the ion(s) across the membrane is facilitated diffusion, and is coupled with the active transport of the molecule(s). In symport, two molecule move in a 'similar direction' at the 'same time'.