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Photodynamic therapy (PDT) is a form of phototherapy involving light and a photosensitizing chemical substance used in conjunction with molecular oxygen to elicit cell death (phototoxicity). [ 1 ] PDT is used in treating acne , wet age-related macular degeneration , psoriasis , and herpes .
Eye is a monthly peer-reviewed medical journal covering ophthalmology. It was established in 1881 as the Transactions of the Ophthalmological Societies of the United Kingdom, obtaining its current name in 1987. [1] It is published by Springer Nature and is the official journal of the Royal College of Ophthalmologists.
Current Eye Research is a medical journal covering all areas of ophthalmology. Areas covered include: clinical research, anatomy, physiology, biophysics, biochemistry, pharmacology, developmental biology, microbiology, and immunology
Photodynamic therapy (PDT) is a form of phototherapy using nontoxic light-sensitive compounds (photosensitizers) that are exposed selectively to light at a controlled wavelength, laser intensity, and irradiation time, whereupon they generate toxic reactive oxygen species (ROS) that target malignant and other diseased cells.
While blue light therapy has similar mechanisms for skin enhancement as red light therapy, its usage for photodynamic therapies in treating cancer are slightly different. Blue light therapy stimulates immune system defences, destroys blood vessels that help cancer cells grow, and causes cell death by reacting with oxygen. [ 16 ]
On June 6, 2016, The American Academy of Ophthalmology announced plans to launch Ophthalmology Retina as an extension of the journal Ophthalmology. [1] This new journal was planned in response to the growing volume of research within the retina subspecialty of ophthalmology, and will be a print and online publication.
The efficacy of antimicrobial photodynamic therapy, using various distinct photosensitizers, has been studied since the 1990s. [ 9 ] [ 7 ] Most studies have yielded positive outcomes, often achieving disinfection levels, as defined by infection control guidelines, exceeding 5 log 10 (99.999%) of microbial inactivation. [ 14 ]
Photoimmunotherapy (PIT) is an oncological treatment that combines photodynamic therapy of tumor with immunotherapy treatment. Combining photodynamic therapy with immunotherapy enhances the immunostimulating response and has synergistic effects for metastatic cancer treatment. [1] [2] [3]